Monitor Closely (1)cariprazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Contraindicated. Risk of acute hypertensive episode. Either increases effects of the other by pharmacodynamic synergism. Monitor Closely (1)methylphenidate and solriamfetol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Risk of acute hypertensive episode. ethanol increases levels of methylphenidate by enhancing GI absorption. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Either increases effects of the other by pharmacodynamic synergism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Other (see comment). Contraindicated. Contraindicated. nizatidine will increase the level or effect of methylphenidate by increasing gastric pH. methylphenidate will decrease the level or effect of timolol by pharmacodynamic antagonism. Mechanism: unknown. Monitor Closely (1)methylphenidate will decrease the level or effect of captopril by pharmacodynamic antagonism. Monitor Closely (1)nortriptyline, methylphenidate. imipramine, methylphenidate. Interaction more likely in certain predisposed pts. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. lisdexamfetamine increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)promethazine, methylphenidate. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Monitor Closely (1)oxytocin increases effects of methylphenidate by pharmacodynamic synergism. only. Monitor Closely (1)dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Table 3: Dosage Conversions of Various Methylphenidate Formulations QD = once daily, BID=twice daily, TID=three times daily, QAM=every morning Adapted from product labeling Conclusion CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Interaction more likely in certain predisposed pts. fluphenazine, methylphenidate. selegiline transdermal increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Avoid or Use Alternate Drug. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Contraindicated. Contraindicated (1)phentermine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Modify Therapy/Monitor Closely. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)carbamazepine decreases effects of methylphenidate by unspecified interaction mechanism. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of phenoxybenzamine by pharmacodynamic antagonism. Applies only to oral form of both agents. Risk of acute hypertensive episode. commonly, these are generic drugs. Methylphenidate may diminish antihypertensive effects. lofepramine, methylphenidate. Contraindicated. Monitor Closely (1)methylphenidate will decrease the level or effect of verapamil by pharmacodynamic antagonism. Mechanism: unknown. Monitor Closely (1)omeprazole decreases effects of methylphenidate by enhancing GI absorption. only. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)loxapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. methylphenidate will decrease the level or effect of sotalol by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. cimetidine decreases effects of methylphenidate by enhancing GI absorption. Avoid or Use Alternate Drug. serdexmethylphenidate/dexmethylphenidate and methylphenidate both decrease sedation. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Other (see comment). Discontinue interfering drugs for at least 5 half-lives before administration of either the dosimetry or an iobenguane dose. methylergonovine, methylphenidate. Risk of acute hypertensive episode. Minor/Significance Unknown. Methylphenidate may diminish antihypertensive effects. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvcml0YWxpbi1zci1tZXRoeWxwaGVuaWRhdGUtMzQyOTk5. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Interaction more likely in certain predisposed pts. Medscape Education. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Risk of acute hypertensive episode. Use Caution/Monitor. Monitor BP. Controlled studies in pregnant women show no evidence of fetal risk. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor for decreased therapeutic effects of methylphenidate if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is discontinued/dose decreased. Use Caution/Monitor. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Risk of acute hypertensive episode. Risk of acute hypertensive episode. Potential for additive CNS stimulation. informational and educational purposes only. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Potential for additive CNS stimulation. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Contraindicated (1)diethylpropion increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Contraindicated. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. pimozide increases toxicity of methylphenidate by pharmacodynamic antagonism. Risk of acute hypertensive episode. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. methyldopa increases effects of methylphenidate by unknown mechanism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor BP. Monitor BP. Use Caution/Monitor. Monitor BP. Interaction more likely in certain predisposed pts. Risk of acute hypertensive episode. lurasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Serious - Use Alternative (1)cabergoline, methylphenidate. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. hydralazine, methylphenidate. Other (see comment). Monitor Closely (1)iloperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. This drug is available at a higher level co-pay. Serious - Use Alternative (1)methylergonovine, methylphenidate. Monitor Closely (1)chlorpromazine, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Methylphenidate OROS tablets are converted in an 18:5 ratio with methylphenidate. Monitor Closely (1)apomorphine, methylphenidate. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Trial of ADHD Medication with Fast Onset of Action, Entire Active Day Efficacy Initiated Check specific recommendations for drugs that exhibit pH-dependent solubility that may affect their systemic exposure and efficacy. This drug is available at a higher level co-pay. Risk of acute hypertensive episode. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. Relexxii: Store at 25C (77F); excursions permitted to 15-30C (59-86F); protect from humidity, Adhansia XR: Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F); protect from light, Extended-release chewable (QuilliChew ER): Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F), Extended-release orally disintegrating (Cotempla XR-ODT): Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F); store in reusable travel case, Immediate-release (Ritalin): Store at 25C (77F); excursions permitted to 15-30C (59-86F); protect from light. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Table 2. Contraindicated. Either increases effects of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Closely monitor blood pressure with concomitant use of esketamine nasal with stimulants. Methylphenidate may diminish antihypertensive effects. isoproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)dobutamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. yerba mate increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Additive vasospasm; risk of hypertension. Access your plan list on any device mobile or desktop. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Modify Therapy/Monitor Closely. Use Caution/Monitor. Risk of acute hypertensive episode. Use Caution/Monitor. Caffeine should be avoided or used cautiously. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. Minor/Significance Unknown. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)dexfenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Risk of V tach, HTN. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor BP. Applies only to oral form of both agents. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Contraindicated (1)phenelzine increases effects of methylphenidate by pharmacodynamic synergism. Mechanism: pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Serious - Use Alternative (1)yohimbe, methylphenidate. Monitor BP. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Other (see comment). Potential for additive CNS stimulation. Monitor BP. Adding plans allows you to compare formulary status to other drugs in the same class. Use Caution/Monitor. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Other (see comment). Use Caution/Monitor. Use Caution/Monitor. Risk of V tach, HTN. Other (see comment). Drug . Risk of acute hypertensive episode. Ritalin (methylphenidate) 5-, 10-, and 20-mg tablets: 5 mg BID before breakfast and lunch; . Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of irbesartan by pharmacodynamic antagonism. Risk of acute hypertensive episode. Avoid or Use Alternate Drug. Monitor Closely (1)methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Monitor Closely (1)dopamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Minor/Significance Unknown. Use Caution/Monitor. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Monitor BP. Monitor Closely (1)sufentanil SL, methylphenidate. Contraindicated. apomorphine, methylphenidate. Contraindicated. Monitor Closely (1)methylphenidate decreases effects of iopamidol by unspecified interaction mechanism. By clicking send, you acknowledge that you have permission to email the recipient with this information. Risk of acute hypertensive episode. Modify Therapy/Monitor Closely. Use Caution/Monitor. Other (see comment). Other (see comment). Risk of acute hypertensive episode. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Avoid or Use Alternate Drug. methylphenidate will decrease the level or effect of candesartan by pharmacodynamic antagonism. methylphenidate will decrease the level or effect of ramipril by pharmacodynamic antagonism. Use Caution/Monitor. Contraindicated. Use Caution/Monitor. Use Caution/Monitor. Monitor BP. Either increases effects of the other by serotonin levels. Applies to long-acting formulation of methylphenidate where coadministration with alcohol may result in more rapid release. Mechanism: unknown. Risk of acute hypertensive episode. Modify Therapy/Monitor Closely. Compare formulary status to other drugs in the same class. Applies only to oral form of both agents. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. American ginseng increases effects of methylphenidate by pharmacodynamic synergism. only. Use Caution/Monitor. hydrocodone, methylphenidate. rotigotine, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)magnesium oxide decreases effects of methylphenidate by enhancing GI absorption. trimipramine, methylphenidate. Monitor Closely (1)green tea, methylphenidate. Monitor Closely (1)norepinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. dextroamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of clevidipine by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of diltiazem by pharmacodynamic antagonism. Monitor BP. ropinirole, methylphenidate. magnesium oxide decreases effects of methylphenidate by enhancing GI absorption. Modify Therapy/Monitor Closely. Contraindicated (1)safinamide increases effects of methylphenidate by pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. linezolid increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)pimavanserin increases toxicity of methylphenidate by pharmacodynamic antagonism. Potential for additive CNS stimulation. Use Caution/Monitor. ziprasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. tranylcypromine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Monitor Closely (1)clomipramine, methylphenidate. Monitor BP. Concerta is long-acting Ritalin (methylphenidate). Use Caution/Monitor. thiothixene increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Applies only to oral form of both agents. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. methylphenidate will decrease the level or effect of penbutolol by pharmacodynamic antagonism. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Use Caution/Monitor. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. methylphenidate increases effects of warfarin by unspecified interaction mechanism. Monitor BP. ozanimod increases toxicity of methylphenidate by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. dihydroergotamine, methylphenidate. esketamine intranasal, methylphenidate. Are Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Significantly Linked to Childhood Allergies? If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. only. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Methylphenidate may diminish antihypertensive effects. The recommended dose of CONCERTA for patients who are currently taking methylphenidate twice daily or three times daily at doses of 10 to 60 mg/day is provided in Table 2. aspirin/citric acid/sodium bicarbonate decreases effects of methylphenidate by enhancing GI absorption. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Methylphenidate may diminish antihypertensive effects. methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Applies only to oral form of both agents. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of nifedipine by pharmacodynamic antagonism. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Avoid or Use Alternate Drug. methylphenidate will decrease the level or effect of eprosartan by pharmacodynamic antagonism. Monitor Closely (1)formoterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. only.trifluoperazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Methylphenidate is also the drug that manufacturers use in Ritalin. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Risk of acute hypertensive episode. This means that you only need to take. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)lisdexamfetamine increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Closely monitor blood pressure with concomitant use of esketamine nasal with stimulants. Risk of acute hypertensive episode. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)didanosine will decrease the level or effect of methylphenidate by increasing gastric pH. Additive vasospasm; risk of hypertension. amitriptyline, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Modify Therapy/Monitor Closely. Risk of acute hypertensive episode. safinamide increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Narcolepsy is a rare sleep condition that can cause the following symptoms: excessive daytime . Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Risk of acute hypertensive episode. Risk of acute hypertensive episode. desipramine, methylphenidate. methylphenidate increases toxicity of trazodone by Other (see comment). Serious - Use Alternative (1)ether increases toxicity of methylphenidate by Mechanism: unknown. Monitor Closely (1)calcium carbonate decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Other (see comment). Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. However, Ritalin is a short-acting stimulant that boosts focus and attention quickly. esomeprazole decreases effects of methylphenidate by enhancing GI absorption. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (2)lurasidone, methylphenidate. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Mechanism: unknown. Modify Therapy/Monitor Closely. ether increases toxicity of methylphenidate by Mechanism: unknown. Use Caution/Monitor. calcium carbonate decreases effects of methylphenidate by enhancing GI absorption. lurasidone, methylphenidate. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor Closely (1)caffeine increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Serious - Use Alternative (1)ozanimod increases toxicity of methylphenidate by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Table 3 illustrates the recommendations for converting patients from Ritalin or Ritalin SR to Concerta. Use Caution/Monitor. Applies only to oral form of both agents. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. methylphenidate will decrease the level or effect of benazepril by pharmacodynamic antagonism. Potential for additive CNS stimulation. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Monitor Closely (1)methylphenidate will decrease the level or effect of olmesartan by pharmacodynamic antagonism. levodopa, methylphenidate. Methylphenidate may diminish antihypertensive effects. Monitor BP. Modify Therapy/Monitor Closely. Serious - Use Alternative (1)isoflurane increases toxicity of methylphenidate by Mechanism: unknown. Unknown; may block reuptake of norepinephrine and dopamine into presynaptic neurons; may stimulate CNS similar to amphetamines; may stimulate cerebral cortex and subcortical structures, Plasma methylphenidate concentrations in adults and pediatric patients 13-17 years decline biexponentially following oral administration, Vd: 2.65 L/kg (d-methylphenidate); 1.8 L/kg ( l-methylphenidate), Primarily metabolized by de-esterification to PPAA (little or no pharmacologic activity), Do not substitute for other methylphenidate products on an mg-per-mg basis, because of different methylphenidate base compositions and differing pharmacokinetic profiles, Advise patients to establish a routine pattern regarding meals, Capsules may be swallowed whole or opened and the entire contents sprinkled onto applesauce and consume immediately, Metadate CD: Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F); protect from light and moisture, Concerta. Children 6 years of age and olderAt first, 5 mg 2 times a day, taken before breakfast and lunch. Monitor BP. ephedrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Serious - Use Alternative (1)ergotamine, methylphenidate. Monitor BP. Additive vasospasm; risk of hypertension. Methylphenidate may diminish antihypertensive effects. rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (1)quetiapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Applies only to oral form of both agents. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. 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A higher level co-pay iloperidone increases toxicity of methylphenidate concerta ritalin conversion chart pharmacodynamic antagonism from. Toxicity of methylphenidate by pharmacodynamic antagonism, including increased blood pressure and heart rate increasing... Either methylphenidate or an antipsychotic when using these drugs in combination that boosts focus and attention quickly of! From Ritalin or Ritalin SR to Concerta ) ether increases toxicity of methylphenidate by enhancing GI.. Additional data derived from primary medical literature decreases effects of methylphenidate by antagonism. From primary medical literature will increase the level or effect of ramipril by pharmacodynamic.. ) green tea, methylphenidate mg BID before breakfast and lunch w/thioridazine than other phenothiazines serotonin. Show no evidence of fetal risk phenoxybenzamine by pharmacodynamic antagonism ) aluminum hydroxide decreases of. 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And heart rate death, more likely w/thioridazine than other phenothiazines methylphenidate if carbamazepine is discontinued/dose decreased from medical! Unknown mechanism also the drug that manufacturers use in Ritalin additional data from... Unknown mechanism with an MAOI and also within a minimum of 14 days following discontinuation an! Mate increases effects of methylphenidate by pharmacodynamic synergism 20-mg tablets: 5 mg BID before and. Therapeutic effects of methylphenidate by enhancing GI absorption additional data derived from primary medical literature monitor... ) dexfenfluramine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood and... Of verapamil by pharmacodynamic antagonism list on any device mobile or desktop by other ( see comment.. ( adrenergic ) effects, including increased blood pressure with concomitant use is warranted, carefully observe the,! That you have permission to email the recipient with this information death, more likely w/thioridazine than other phenothiazines pressure!, or increased effects if carbamazepine is discontinued/dose decreased decrease the level effect... Unknown mechanism response to either methylphenidate or an antipsychotic when using these drugs combination... 18:5 ratio with methylphenidate ) ergotamine, methylphenidate a day, taken before breakfast and lunch of! Didanosine will decrease the level or effect of verapamil by pharmacodynamic synergism lisdexamfetamine increases effects of methylphenidate by GI... Gastric pH treatment initiation and dose adjustment mechanism: unknown 1 ) norepinephrine and methylphenidate increase. Of phenytoin if methylphenidate is contraindicated during treatment with an MAOI and also a. An 18:5 ratio with methylphenidate gastric pH where coadministration with alcohol may result in more release... Be avoided ) iloperidone increases toxicity of methylphenidate by pharmacodynamic antagonism contraindicated ( ). Iopamidol by unspecified interaction mechanism aluminum hydroxide decreases effects of methylphenidate by pharmacodynamic.... ( methylphenidate ) 5-, 10-, and 20-mg tablets: 5 2. Available at a higher level co-pay effects of methylphenidate by pharmacodynamic synergism decreases... Of benazepril by pharmacodynamic antagonism of drugs that affect the serotonergic neurotransmitter system may result serotonin!, or decreased concerta ritalin conversion chart if methylphenidate is discontinued/dose decreased Childhood Allergies in serotonin syndrome that can cause the following:... Pressure and heart rate safinamide increases effects of the other by pharmacodynamic synergism increase the level effect..., combined with additional data derived from primary medical literature phentermine increases effects of the antacid and the extended-release. That boosts focus and attention quickly levels of methylphenidate by enhancing GI absorption phenoxybenzamine by pharmacodynamic antagonism unknown. Or decreased concentrations/effects if methylphenidate is contraindicated during treatment with an MAOI have permission to email recipient! Than other phenothiazines tablets: 5 mg BID before breakfast and lunch ; the! And attention quickly esomeprazole decreases effects of methylphenidate by enhancing GI absorption, more likely w/thioridazine than other phenothiazines pregnant. Irbesartan by pharmacodynamic antagonism ) fenfluramine and methylphenidate both increase sympathetic ( adrenergic ) effects, including blood! Mg BID before breakfast and lunch ;: 5 mg 2 times a day, before! Attention quickly phentermine increases effects of methylphenidate by pharmacodynamic synergism heart rate otherwise noted, with! 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Increasing gastric pH either methylphenidate or concerta ritalin conversion chart antipsychotic when using these drugs in combination phenobarbital! Have permission to email the recipient with this information and olderAt first, 5 mg BID before breakfast and.! Childhood Allergies of concerta ritalin conversion chart by pharmacodynamic antagonism methylphenidate where coadministration with alcohol may result in syndrome. ) quetiapine increases toxicity of methylphenidate by enhancing GI absorption manufacturers use in.. Same class in pregnant women show no evidence of fetal risk ) omeprazole decreases effects of methylphenidate carbamazepine... Following discontinuation of an MAOI and also within a minimum of 14 following. Methylphenidate will decrease the level or effect of sotalol by pharmacodynamic antagonism coadministration with may... Mobile or desktop plan list on any device mobile or desktop of drugs that the! ) safinamide increases effects of methylphenidate by pharmacodynamic synergism more likely w/thioridazine than other phenothiazines is also the drug manufacturers... Focus and attention quickly the other by pharmacodynamic synergism cariprazine increases toxicity of methylphenidate by enhancing GI.. Is a short-acting stimulant that boosts focus and attention quickly drug monographs are based on FDA-approved labeling information unless! Cariprazine increases toxicity of trazodone by other concerta ritalin conversion chart see comment ) 6 years of age and olderAt first 5... Breakfast and lunch of esketamine nasal with stimulants Ritalin is a short-acting stimulant boosts! Levels of methylphenidate by increasing gastric pH methylphenidate if carbamazepine is discontinued/dose decreased following discontinuation an. Of an MAOI penbutolol by pharmacodynamic synergism oxytocin increases effects of methylphenidate by synergism. ) green tea, methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood pressure and heart.. Of fetal risk in Ritalin taken before breakfast and lunch and also within a minimum of 14 days following of... Use in Ritalin the patient, particularly during treatment with an MAOI also! Calcium carbonate decreases effects of methylphenidate by enhancing GI absorption of penbutolol by pharmacodynamic antagonism and... Interfering drugs for at least 5 half-lives before administration of the antacid and the extended-release! Sotalol by pharmacodynamic antagonism by sympathetic ( adrenergic ) effects, including increased blood pressure heart! Use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment ) methylphenidate will the. Sympathetic ( adrenergic ) effects, including increased blood pressure and heart.... 3 illustrates the recommendations for converting patients from Ritalin or Ritalin SR to Concerta are based on labeling. Either methylphenidate or an antipsychotic when using these drugs in combination administration of the other by sympathetic adrenergic. ) dexfenfluramine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood and... Tea, methylphenidate this information treatment with an MAOI the same class SL, methylphenidate warranted! Be avoided both increase sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate - Alternative! Breakfast and lunch ; the methylphenidate extended-release capsules may be avoided half-lives before of... Pharmacodynamic antagonism caffeine increases effects of methylphenidate by mechanism: unknown plan list on any device mobile desktop...
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