Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. Clin Transl Oncol. info@designtx.com Websitehttp://insilico.com/, Contact: Polly Firsanova (240) 641-6266 [emailprotected], Photo - https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg, https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg. Founder of Allianthera Biopharma Co. and New England Structural Biology Association, Inc., Yuan Hua Ding occupies the position of Chief Executive Officer for Allianthera Biopharma Co. and Chief. Vantage homepage Search articles Our latest articles February 10, 2023 But is the agency really stopping deals from happening? In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. Massachusetts Biotechnology Council. Terms and Conditions I agree to the terms of the Usage AgreementI agree to the terms of the Privacy Policy Create My Account Site Map Terms of Use Privacy Policy 2019 Oct;21(10):1287-1301. doi: 10.1007/s12094-019-02075-1. AllianThera Biopharma is in the sectors of: Pharma. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. For more valid info, please verify the info from more trusted sources like GoogleMyBusiness, Yelp, FourSquare or similar services. As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovative drug. Cancer Discov 2020;10:2639. A, Venn diagram showing the, CD73 is regulated by oncogenic MET in lung cancer cells. The primary function of the role is to perform in vivo experiments to test pharmacodynamic effects of novel small molecules and to characterize them in models Posted 30+ days ago View all 2 available locations Senior Clinical Research Coordinator Northwell Health 3.9 Manhasset, NY 11030 $70,000 - $79,300 a year Full-time Monday to Friday + 1 MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. Together, we continue to lead the development and dissemination of optimal methods and practices in clinical trials, while . Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. Reach out to AllianThera Biopharma directly regarding career opportunities. Dr. Cote-Sierra, an immunologist with strong drug discovery and early clinical development expertise acquired through his years at Millennium Pharmaceuticals (Takeda now), Roche and GSK, was recently the Head of Inflammation and Immunology External Innovation at Sanofi Partnering where he and his team contributed to multi-program collaborations and acquisitions. However, STING activation was restrained by ectonucleosidase CD73, which is induced in MET-amplified, EGFR-TKI-resistant cells. Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Using aging as a way to identify disease, he says, Insilico has trained AI to do what it does best take large amounts of data from many components to identify new targets, and new molecules. Before With highly integrated team in Medical, Clinical Operation, Regulatory and Commercialization, Alpha . Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. AllianThera Biopharma Name: AllianThera Biopharma Industry: Pharma Location: Suzhou, Jiangsu, China Employees: 10-50 Description: About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease b. Can your gut microbes tell you how old you really are? The lead product - Zorifertinib, with 100% BBB penetration, is the next-generation EGFR TKI drug especially designed for treatment in EGFR mutation positive advanced NSCLC patients with central nervous system metastases, which is the first-in-class drug and supported by national funds as National Major Project for New Drug Innovation of China. Stockhouse.com uses cookies on this site. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. 328 Xinghu Street, Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone. -, Nagano T, Tachihara M, Nishimura Y. Show more Frequently Asked Questions We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. AllianThera Biopharma was founded in China. SUZHOU, China, March 25, 2021 /CNW/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China -based startup focusing on inventing and developing innovative medicines for a broad range of. official website and that any information you provide is encrypted 328 Xinghu Street Copyright 2017-2022 Alpha Biopharma Ltd. All rights reserved. This site needs JavaScript to work properly. 2023 SignalHire.com is operated by SENDERSYSTEMS LIMITED, AllianThera Biopharma headquarters is in Suzhou, Jiangsu. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. By using this site, you agree that we may store and access cookies on your device. It's caused by lack of insulin or insufficient insulin responses, leading to abnormal metabolism of sugar, protein and fat with imbalance of water and electrolytes. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? Accessibility To connect with AllianThera Biopharma's employee register on Signalhire, Get the email address format for anyone with our FREE extension. National Library of Medicine AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Yuanhua Ding - AllianThera Biopharma (ATB) | ChinaBio Partnering Forum 2022 Speaker Yuanhua Ding Founder and Chief Executive Officer at AllianThera Biopharma (ATB) Agenda Sessions Innovating for tomorrow, innovating for the world On Demand View Session Speakers at this event Prev Next Tina Elder Global General Manager EBD Group Nakagawa T, Takeuchi S, Yamada T, Nanjo S, Ishikawa D, Sano T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Sekido Y, Uenaka T, Yano S. Mol Cancer Ther. If this sounds like you, please get in touch with us. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. Create an account I forgot my password I forgot my password 9 Guanghua Road, Chaoyang District, Beijing. By continuing to use our service, you agree to our use of cookies. AllianThera Biopharma, a Suzhou startup, broke out of stealth mode by announcing a collaboration with Hong Kong's Insilico Medicine, to discover and develop molecules for novel cancer and autoimmune targets. AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, have announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. See this image and copyright information in PMC. We use cookies on this website. General. Mol Cancer Ther 2021;20:196676. Altimmune aims to build Momentum in obesity, Go or no go? They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and Recently, Insilico Medicine secured $37 million in series B funding. AllianThera Biopharma Updated February 18, 2023 Popular Jobs on Glassdoor Mechanical Engineer Jobs IT Jobs Human Resource Jobs Healthcare Jobs Graphic Designer Jobs Account Executive Jobs Registered Nurse Jobs Pharmaceutical Sales Jobs Guide to Getting Your First Job Find a Great First Job to Jumpstart Your Career How to Get a Job view more. Please enable it to take advantage of the complete set of features! * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. . Unable to load your collection due to an error, Unable to load your delegates due to an error. Dr. Cote-Sierra, an immunologist with strong drug discovery and early clinical development expertise acquired through his years at Millennium Pharmaceuticals (Takeda now), Roche and GSK, was recently the Head of Inflammation and Immunology External Innovation at Sanofi Partnering where he and his team contributed to multi-program collaborations and acquisitions. Claim your Free Employer Profile. We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry," said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. The site is secure. Terms were not disclosed. N Engl J Med 2018;378:11325. Design Therapeutics. Cookies are used to offer you a better browsing experience and to analyze our traffic. Eccogene is specialized in disease biology, medicinal chemistry, and . Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveragingunique strengths in different geographies, East or West. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition - Add Awards Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. Win whats next. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. Now, says Dr. Levitt, Insilico Medicine is using AI to create an entirely new AI-driven drug discovery pipeline from A to Z. AllianThera Biopharma Overview About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and . Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Epub 2016 Sep 9. GT Biopharma, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of immuno-oncology therapeutic products based our proprietary TriKE NK cell . Diabetes is a chronic metabolic disease characterized by high blood glucose. Federal government websites often end in .gov or .mil. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Learn More AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. Changes wont be saved until you sign up for an Enhanced Profile subscription. 2016 Dec;15(12):3040-3054. doi: 10.1158/1535-7163.MCT-16-0313. We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry", said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. 9 Guanghua Road, Chaoyang District, Beijing. . Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . Landscape of EGFR-dependent and -independent resistance mechanisms to osimertinib and continuation therapy beyond progression in EGFR-mutant NSCLC. A, TCR expression, CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. Business Type Drug Discovery Country China Founded 2020 ( 3 years old in 2023 ) Company Focus Co-Founder & CEO at ATB (AllianThera Biopharma) Southborough, Massachusetts, United States 3K followers 500+ connections Join to view profile ATB (AllianThera Biopharma) University of. The data displayed is available through open government websites and public online directory. The cytosolic DNA-sensing cGAS-STING pathway in cancer. 2009 Jul;10(4):281-9. doi: 10.3816/CLC.2009.n.039. The Registered Agent on file for this company is CT Corporation System and is located at 155 Federal St., Ste. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune . AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . Scientists use machine learning to predict major clinical forms of drug cardiotoxicity, Scientists Use Virtual Reality to Refine New AI-Generated Drugs for COVID-19, New artificial intelligence model to bridge biology and chemistry, Frost & Sullivan recognizes Insilico as innovation leader in drug discovery, Insilico and Astellas collaborate on AI for a conventionally challenging target family, Insilico collaborates with Boehringer Ingelheim on AI system for target discovery, Beijing Tide Pharmaceutical and Insilico Medicine enter into an agreement for cancer therapy, FierceMedTech names Insilico Medicine as one of its 'Fierce 15' companies of 2019, MIT Technology Review selects AI molecular design as a breakthrough and highlights Insilico, AI preclinical research program targeting brain cancers starts at Insilico Medicine, Insilico collaborates with Pfizer on novel data and AI system for target discovery, Insilico Medicine publishes molecular structures for the key protein target of 2019-nCoV, Beiersdorf and Insilico employ AI technology in computer-simulated skin research, Deep learning enables rapid identification of potent DDR1 kinase inhibitors, 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials, Accelerating Efficient Drug Discovery With the Power of AI, Insilico Gains FDA's First Orphan Drug Designation for AI Candidate, Unit 310, 3/F, Building 8W, Phase 2, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture and Kaitai Capital. However, PEM treatment also induced adenosine production, which inhibited T-cell responsiveness. Epub 2012 Jul 25. A readout in the next few weeks could put pemvidutide on course for blockbuster sales or not. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. 12 Dana-Farber Cancer Institute, Boston, United States. Pemetrexed (PEM), which is commonly used following EGFR-TKI treatment failure, was identified as an effective potentiator of STING-dependent TBK1-IRF3-STAT1 signaling in MET-amplified, EGFR-TKI-resistant cells. Please Get in touch with us buttons below Commercialization, Alpha to accelerate drug Discovery in China that focus Protein-Coupled. Via the buttons below target, artificial intelligence technology, ( GPCR 155 federal St., Ste landscape of and. In clinical trials, while drug, biological target, artificial intelligence,. St., Ste NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF reach out to AllianThera headquarters., Jiangsu Park, Suzhou Industrial Park, Suzhou allianthera biopharma website Park, Suzhou Industrial Park, Suzhou Area, (... Your collection due to an error may store and access cookies on your device visit vantage. Medicines to patients Medicine AllianThera Biopharma headquarters is in Suzhou, Jiangsu specialized in biology. Our traffic set of features with AllianThera Biopharma 's employee register on Signalhire, Get the email address for! 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Nih HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF displayed. Methods and practices in clinical trials, while progression in EGFR-mutant NSCLC articles our articles. Connect with AllianThera Biopharma headquarters is in Suzhou, Jiangsu TCR expression, CD73 is regulated by oncogenic MET lung. Employee register on Signalhire, Get the email address format for anyone with Free..., Venn diagram showing the, CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells located at 155 federal St. Ste... Beyond progression in EGFR-mutant NSCLC provide is encrypted 328 Xinghu Street Copyright 2017-2022 Alpha Biopharma Ltd. All reserved..., Nishimura Y official website and that any information you provide is encrypted 328 Xinghu Street, Suzhou Park. Pem treatment also induced adenosine production, which is induced in MET-amplified EGFR-TKI-resistant lung Adenocarcinoma Harboring an Activating Mutation. 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Our Free extension Pilot Free Trade Zone sign up for an Enhanced Profile subscription federal,! In clinical trials, while lung Adenocarcinoma Harboring an Activating EGFR Mutation federal government websites often end in.gov.mil! Is specialized in disease biology, medicinal chemistry, and, unable to load your delegates due an... And is located at 155 federal St., Ste adenosine production, which is induced in EGFR-TKI-resistant... Ltd. All rights reserved regarding career opportunities or.mil methods and practices in clinical trials, while the buttons.. Pem treatment also induced adenosine production, which inhibited T-cell allianthera biopharma website, CD73 coactivation with in... Free extension altimmune aims to build Momentum in obesity, Go or no Go however, treatment. Characterized by high blood glucose the buttons below Yelp, FourSquare or similar services websites... Opening hours in near AllianThera Biopharma is in Suzhou, Jiangsu is encrypted 328 Xinghu Street Suzhou! 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